My Patients Ask — What do you recommend for preventing and treating COVID?

First of all, I strongly recommend preventing it by getting one of the two mRNA COVID vaccines. For treatment outside the hospital, there is now a fairly safe and effective treatment.

It is an infusion of a COVID-19 antibody combo which has now been shown to dramatically reduce the need for hospitalization and to reduce fatality rates.

Regeneron’s monoclonal antibody cocktail, called “REGEN-COV,” consisting of casirivimab and imdevimab, reduced viral load, symptom duration, hospitalization, and mortality among 4,567 non-hospitalized patients with severe COVID-19 and at least one risk factor for severe COVID-19, according to data from a late-stage trial.

The results were presented at the American Thoracic Society International Conference.

Julie Philley, MD, pulmonary critical care physician and chair of internal medicine at the University of Texas Health Sciences Center, Houston, said that a single IV dose of the medication, compared with placebo, “significantly reduced hospitalizations or death by 70%, significantly shortened duration of symptoms by 4 days, and the results were consistent across subgroups, including those with high baseline viral load who have been shown to have a poor prognosis with [a] higher incidence of hospitalizations and longer symptom duration,”

REGEN-COV is an investigational monoclonal antibody cocktail that is authorized for emergency use in the United States in patients with mild to moderate COVID-19 at high risk for severe disease or hospitalization. The cocktail is administered intravenously.

REGEN-COV is also being assessed in other settings.

In April, Regeneron announced positive results of a phase 3 trial that showed REGEN-COV prevented COVID-19 infection in household contacts of individuals infected with SARS-CoV-2. Read about that trial here.


This blog was accurate as of the day of posting. However, as the COVID-19 pandemic rapidly evolves and the scientific community’s understanding of the novel coronavirus and the COVID vaccine develops, the information above may have changed since it was last updated. While I aim to keep all of my blogs on COVID and the COVID vaccine up to date, please visit online resources provided by the CDC, WHO, and your local public health department to stay informed on the latest news.

© Copyright WLL, INC. 2021. This blog provides a wide variety of general health information only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment from your regular physician. If you are concerned about your health, take what you learn from this blog and meet with your personal doctor to discuss your concerns.

 

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