Increasing HDL cholesterol levels may not impact heart disease risk

In a front-page story, the New York Times reports that “a new study that makes use of powerful databases of genetic information has found that raising HDL” cholesterol “levels may not make any difference to heart disease risk.”

The Boston Globe reports on its front page, “In the study appearing in the medical journal The Lancet, a team led by researchers from Massachusetts General Hospital and the Broad Institute examined the health of more than 100,000 people, some of them with genetic variations that elevated their levels of HDL.”

The researchers “found that those variations did not protect against heart attacks.”

MedPage Today reports, “In an accompanying editorial, Steve Humphries, PhD, of University College London, and colleagues noted that the study is consistent with previous mendelian randomization analyses focused on the same issue and adds to an increasing number of mendelian randomization studies of coronary heart disease biomarkers.”

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