My Patients Ask — Should people on oral steroids not take the COVID vaccine?

A physician wrote this to the American Academy of Allergy, Asthma, and Immunology, “I assume with high dose steroids (>20mg/day) for prolonged periods, that the COVID vaccine should be deferred until at least several weeks. Any guidance with low dose or IM steroids and timing of COVID-19 vaccine?”

The AAAAI responded, “Daily oral steroids may interfere with the antibody response to the vaccine based on data with other immunosuppressives and flu vaccine.

“If the dose can be safely stopped, then waiting two weeks may be a reasonable approach.

“If the steroids cannot be stopped, we would not delay administration of the vaccine as the risks associated with COVID infection outweigh the potential impaired response.”


This blog was accurate as of the day of posting. However, as the COVID-19 pandemic rapidly evolves and the scientific community’s understanding of the novel coronavirus and the COVID vaccine develops, the information above may have changed since it was last updated. While I aim to keep all of my blogs on COVID and the COVID vaccine up to date, please visit online resources provided by the CDC, WHO, and your local public health department to stay informed on the latest news.

© Copyright WLL, INC. 2021. This blog provides a wide variety of general health information only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment from your regular physician. If you are concerned about your health, take what you learn from this blog and meet with your personal doctor to discuss your concerns.

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