The herbal remedy St. John’s Wort effectively treats symptoms of major depression, an analysis of previous studies found on Wednesday. St. John’s Wort extracts tested in the different trials were better than placebos and as effective as standard antidepressants with fewer side effects, the researchers reported in the Cochrane review, a journal that analyses medical and scientific studies.

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MedPage is reporting a systematic Cochrane review concluding that breast self-examination does not reduce breast cancer mortality and may cause harm by prompting unnecessary biopsies. This recommendation is based upon studies that include almost 400,000 women.

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