Tag Archives: adult stem cells

Patients’ own stem cells used to reverse heart damage

A story on research involving the use of stem cells to repair damaged hearts received a significant amount of coverage, particular on all of the network news broadcasts, where it received more coverage, with regard to time, than any other story on the broadcasts the entire week.. Continue reading

Adult Stem Cells, Not Embryonic, Helping Patients With Multiple Sclerosis

A groundbreaking new study provides more good news for treatment of multiple sclerosis (MS) with adult stem cells. Researchers at the University of Bristol used patients’ own adult stem cells to treat their MS.

In a Phase I clinical trial, six patients with MS were treated with their own bone marrow adult stem cells and their progress followed for one year. The treatment appeared to stabilized the patients’ condition and showed some benefits. As one measure of the success of the procedure, damaged nerve pathways were able to carry electrical pulses more effectively after the treatment.

Multiple sclerosis is an incurable disease, with the patient’s own immune system attacking the central nervous system and eventually leaving many patients in a wheelchair.

One of the most encouraging aspects of this trial was the elegantly simple procedure. Patients reported to the hospital and had bone marrow adult stem cells removed, the cells were filtered, and then given back to the patients intravenously. The patients went home before the end of the day.

The research team is led by Professor Neil Scolding, at the University of Bristol and North Bristol NHS Trust. Professor Scolding said:

“We are encouraged by the results of this early study. The safety data are reassuring and the suggestion of benefit tantalising. Research into the underlying mechanisms is ongoing and vital, in order to build on these results. We believe that stem cells mobilised from the marrow to the blood are responsible, and that they help improve disease in several ways, including neuroprotection and immune modulation.”

The team is now planning a Phase II/III study. The report for this trial is published in the Nature journal Clinical Pharmacology & Therapeutics.

Previous studies have also had good success at stopping MS progression, and in some cases putting patients into remission. Dr. Richard Burt at Northwestern University has published several studies showing good success using adult stem cells to “reboot”  the immune system of MS patients.

Scientists in Australia have also used the procedure with success, and recently Dr. Mark Freedman of Ottawa, Canada has produced “long-lasting remission” in MS patients.

In these cases, patients had their bone marrow adult stem cells collected, then received chemotherapy to knock the rogue immune cells that were attacking their nervous system. Then their adult stem cells were re-injected.

While recent successful treatments have used milder chemotherapy, this is still not a gentle or risk-free procedure for the patient.

The new approach by the Bristol team is all the more interesting in this respect, because there is no pre-conditioning with chemotherapy.

An international group of multiple sclerosis researchers have looked at these uses of adult stem cells for treatment of MS, and propose moving forward with additional clinical trials to help patients.

Placenta-derived stem cell therapy may benefit patients with Crohn’s disease

The successes for adult, cord blood, and placental-derived stem cells just keep piling up. Now comes an AP report saying, “Celgene Corporation … reported a successful safety trial of a placenta-derived stem cell therapy as a treatment for Crohn’s disease.”

During the trial, “12 patients with moderate to severe Crohn’s disease,” who had been previously treated unsuccessfully, “were given two infusions of Celgene’s PDA-001 at one week apart, at one of two doses.”

According to Celgene, patients who received a lower-dose of PDA-001 appeared to benefit from the treatment and clinical remission was noted in four participants, Reuters reported.

Such findings were considered so encouraging that the firm has decided to test the therapy on a broad spectrum of diseases.

What’s more, PDA-001 is unlikely to draw ire, because it is cultivated from healthy, full-term human placental tissue.

Could this be another death knell for the unwise and unethical research on stems cells taken from unborn human children? I could only hope and pray so.

Adult Stem Cells from Fat Tissue Offer Hope for MS Treatment

Let’s see: how many stories have you seen in the news about embryonic stem cells helping even one human being? Uh . . .  none. And, how many stories have you seen about adult stem cells helping humans? Hundreds. Do you see a pattern developing here? And, today there’s another story in the news about adult stem cells.

More Information: Continue reading

Adult Stem Cell Research Has Yet Another Victory – Helps Type 1 Diabetics

New research using adult stem cells is showing further insulin independence for Type 1 diabetes patients. The study, led by Richard Burt of Northwestern University’s Feinberg School of Medicine in Chicago, is the second in the last two years to show significant progress in diabetes using the noncontroversial stem cells.

More Information: Continue reading

Doctor Mehmet Oz Tells Oprah’s Audience Embryonic Stem Cell Research Debate is Dead

Readers of this blog know the many reasons that we should abandon even considering experimenting with embryonic stem cells. Now, Dr. Mehmet Oz, a cardiovascular surgeon at Columbia University and a regular on Oprah Winfrey’s popular eponymous television program, is agreeing with me that embryonic stem cell research is obsolete.

More Information: Continue reading

First-Ever Treatment of Stroke Using Adult Stem Cells (another reason embryonic stem cell research is doomed)

In what is believed to be the nation’s first such procedure, doctors in Texas were able to successfully use adult stem cells from a patient to treat the effects of his stroke. Physicians from Memorial Hermann-Texas Medical Center and the University of Texas Medical School at Houston were involved in the process.

More Information: Continue reading

Healing for the Holidays: Adult Stem Cell Research Still Outpaces Embryonic by Miles and Miles and Miles …

Today we seem to be floating on a tattered raft of bad news, but this is a week for Thanksgiving, and it seems only right to note that for all the trouble we face, we live in the most blessed times in human history. This is also an extraordinary era for medicine. As we count our blessings this week, consider what one field – adult stem cell research and therapy – is accomplishing for human healing.

More Information: Continue reading

Ethical Stem Cell Research Helps Scientists Study Genetic Disorders

CitizenLink is reporting that stem cells created ethically from adult cells are allowing researchers at the Harvard Stem Cell Institute to watch the development of 10 genetic disorders in a lab dish.

My Take? Continue reading

Adult Stem Cells Treat Lung Disease

CitizenLink.org is reporting that two Canadians have been injected with a genetically modified version of their own adult stem cells in an attempt to cure pulmonary hypertension, a rare, debilitating lung disease. The procedure, which has successfully cured rats with pulmonary hypertension, has halted the progress of the disease in the patients. The first patient, who has had the disease for 13 years, is reporting no ill effects from the treatment and has seen her condition improve.

My Take? Continue reading

Adult Stem Cells Show Promise for Healing Broken Bones

CitizenLink is reporting that researchers at the University of North Carolina have used adult stem cells to improve the healing of broken bones in mice.

Dawn Vargo, bioethics analyst for Focus on the Family Action, said: “Although this particular treatment is still being tested in mice, it might soon be added to the long list of adult stem-cell treatments successfully used in people suffering from debilitating.” Continue reading

It’s time to stop wasting money on embryonic stem cell research

In a stunning news story, “Scientists Admit Embryonic Stem Cell Research Hasn’t Been Successful,” Lord Patel of Dunkeld, the chairman of the United Kingdom National Stem Cell Network and a chancellor at Dundee University, says “embryonic stem cell research is simply not working.”

As I’ve pointed out in media interviews for years, embryonic stem cell research has not been used to help a single person and is siphoning off research dollars that could be used to further adult stem cell research. Continue reading