What about COVID-19 and melatonin?

Long-time readers know that my “go-to” sources for natural medicines (herbs, vitamins, and supplements) are ConsumerLab.com and Natural Medicines(TM). ConsumerLab has posted about coronavirus and melatonin:

Melatonin is a hormone that helps regulate sleep and can trigger sleep in people with sleep disorders.

Melatonin has also been suggested on some websites as a potential treatment in COVID-19, although there are no reports of such use or of a proven benefit. 

Rationale for use of melatonin in COVID-19 appears to stem from the fact that it can affect immune responses.

Experiments in mice, for example, have shown melatonin to increase levels of certain cytokines (immune-regulating molecules) in those infected with various viruses and to reduce virus-related mortality, but this benefit has yet to be demonstrated in human clinical trials.

Another rationale given for use of melatonin in treating COVID-19 is that melatonin levels fall with older age, and older age is a risk factor for COVID-19 (as it is for many diseases).

Interestingly, studies have shown decreased melatonin levels in people with various advanced diseases, but melatonin has not been shown to decrease with age in healthy individuals. 

ConsumerLab has tested the quality of a wide variety of melatonin supplements on the market and has published its Top Picks in its Melatonin Supplements Review, which contains additional information about using melatonin, including potential side effects.

Typical dosage for sleep is 0.3 mg to 3 mg about 30 to 60 minutes before bedtime. 

Of course, the most important thing you can do to avoid infection with coronavirus is to prevent exposure by following the latest recommendations of the CDC and World Health Organization and take steps to stay healthy, including getting adequate sleep, keeping up with your daily exercise, and eating a healthy nutritious diet. 

© Copyright WLL, INC. 2020. This blog provides a wide variety of general health information only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment from your regular physician. If you are concerned about your health, take what you learn from this blog and meet with your personal doctor to discuss your concerns.

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