What about COVID-19 and melatonin?

General Health
Long-time readers know that my "go-to" sources for natural medicines (herbs, vitamins, and supplements) are ConsumerLab.com and Natural Medicines(TM). ConsumerLab has posted about coronavirus and melatonin: Melatonin is a hormone that helps regulate sleep and can trigger sleep in people with sleep disorders. Melatonin has also been suggested on some websites as a potential treatment in COVID-19, although there are no reports of such use or of a proven benefit.  Rationale for use of melatonin in COVID-19 appears to stem from the fact that it can affect immune responses. Experiments in mice, for example, have shown melatonin to increase levels of certain cytokines (immune-regulating molecules) in those infected with various viruses and to reduce virus-related mortality, but this benefit has yet to be demonstrated in human clinical trials. Another rationale given for use of melatonin…
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